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Advantages of NJ’s Pure Platelet Rich Plasma

Platelet-rich plasma is an autologous blood product composed of concentrated platelets. Numerous studies have demonstrated that the use of autologous PRP in bone regeneration represents a safe, simple, and cost-efficient approach that has positive effects on cell proliferation and migration, osteogenesis, and angiogenesis.

Consequently, the combined use of PRP and β-TCP has gained popularity in the field of bone tissue engineering for the combination of all properties required in an ideal bone graft material, including osteoinductivity, osteoconductivity, osteogenesis, and angiogenesis. You can also buy pure PRP in NJ via https://5linebiologics.com/platelet-rich-plasma/ for your research and business needs.

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Despite the increasing use of PRP, the optimal PRP formulation for tissue regeneration is still unknown, and over the past few years, attention has been drawn to the concentration of leukocytes in PRP. It has been demonstrated that high concentrations of leukocytes in PRP may deliver increased levels of pro-inflammatory cytokines, including interleukin and tumor necrosis factor, and result in the production of destructive proteases, together with the inhibited formation and enhanced degradation of extracellular matrix.

Considering the harmful effects of pro-inflammatory cytokines released from leukocytes on tissue regeneration, the effort has been put into the depletion of the leukocytes in PRP to prepare pure platelet-rich plasma, in an attempt to achieve maximum therapeutic benefit. While the superior effects of P-PRP over L-PRP have been proved on regeneration of articular cartilage, they have not yet been evaluated on bone regeneration.